Weight Loss Shots Cost 2026: Every Injection Priced With and Without Insurance
Wegovy, Zepbound, Mounjaro, Ozempic, Saxenda and compounded GLP-1 injections — retail price, manufacturer-direct price, Costco, telehealth floor, and what insurance actually pays.
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The number you came for
Weight loss shots cost between $69 and $1,349 per month in 2026 depending on three things: brand-name or compounded, which channel you buy from, and whether insurance covers it. The retail cash price ($1,000-$1,349) is a number almost nobody should pay — every manufacturer now sells direct at $349-$499, and licensed telehealth compounders sell the same molecules for $69-$299. Prices below verified October 2026.
Weight loss shot prices by medication
| Injection | Retail cash | Manufacturer direct / warehouse | Compounded (telehealth) | With covered insurance |
|---|---|---|---|---|
| Wegovy (semaglutide 2.4 mg) | ~$1,349 | $349 NovoCare / Costco; $199 first 2 months | $69-$199 as semaglutide | $0-$25 with savings card |
| Ozempic (semaglutide ≤2 mg) | ~$998 | $349 Costco / NovoCare | $69-$199 as semaglutide | $25 with savings card (T2D) |
| Zepbound (tirzepatide) | ~$1,086 | $349-$499 LillyDirect vials by dose | $119-$299 as tirzepatide | $25 with savings card |
| Mounjaro (tirzepatide) | ~$1,080 | No direct program (use Zepbound vials) | $119-$299 as tirzepatide | $25 with savings card (T2D) |
| Saxenda (liraglutide, daily) | ~$1,350 | None | Generic liraglutide ~$470-$600 | Varies; often excluded |
| Compounded semaglutide | — | — | $69 (prepay) to $199 (monthly) | Not covered |
| Compounded tirzepatide | — | — | $119 (prepay) to $299 (monthly) | Not covered |
Provider-by-provider compounded pricing lives in the GLP-1 Price Index; brand-name direct channels are compared in NovoCare vs LillyDirect.
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Cost per shot, not per month
| Scenario | Monthly | Shots / month | Per shot |
|---|---|---|---|
| Wegovy retail | $1,349 | 4 | ~$337 |
| Wegovy NovoCare | $349 | 4 | ~$87 |
| Zepbound LillyDirect 5 mg | $499 | 4 | ~$125 |
| Compounded semaglutide monthly | $119-$199 | 4 | $30-$50 |
| Compounded semaglutide prepay | $69 | 4 | ~$17 |
| Saxenda retail | $1,350 | 30 (daily) | ~$45 |
What drives the price up
- Buying retail with no program. CVS, Walgreens and Walmart cash prices sit at list. The same box is $349 from NovoCare. See CVS, Walgreens and Walmart GLP-1 pricing.
- Membership stacking. Some telehealth brands quote $99-$151 for medication and add a $79-$135 membership. Real cost is $178-$351. The hidden-fee map lists them.
- Dose escalation pricing. Providers like Hims and Yucca charge more as your dose rises ($179→$299). Flat-rate providers do not.
- Prepay traps. The $69 headline requires $828-$1,188 upfront and is usually non-refundable. Compare against month-to-month before committing.
What insurance actually does
Commercial plans mostly cover Ozempic and Mounjaro for type 2 diabetes; about half exclude Wegovy and Zepbound for weight. When covered, the manufacturer savings card takes the copay to $0-$25. Medicare Part D added anti-obesity GLP-1 coverage in 2026 with a $50/month cap for low-income beneficiaries via the Bridge program; savings cards are prohibited on Medicare. Medicaid varies by state. If you are denied, the appeal process succeeds more often than people expect when BMI and comorbidity documentation is complete.
Cheapest route by situation
- Insured, drug covered: savings card → $0-$25/month. Nothing beats this.
- Insured, drug excluded: NovoCare/LillyDirect direct at $349-$499 beats the "not covered" savings-card price (~$650).
- Uninsured, want brand-name: NovoCare $349 ($199 intro) or Costco if a member.
- Uninsured, lowest cost: compounded semaglutide $119 monthly or $69 prepaid from a provider with a clean complaint file.
- Medicare: Bridge program, $50 cap if LIS-eligible.
Compounded semaglutide from $119/month — no insurance needed.
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Lose 15-22% body weight — GLP-1s from $147/month
Compounded semaglutide & tirzepatide prescribed online by US-licensed providers. No insurance needed — medication shipped to your door in 3-5 days.
⚡ Limited spots this month — 50,000+ patients already started
See if I qualify — Free consultationFrom $147/month · No insurance needed · Ships nationwide in 3-5 days · Paid partnership · Results vary
Doctor-backed GLP-1 weight loss from $147/month
Compounded semaglutide & tirzepatide. Online consultation with a US-licensed provider. No insurance needed.
⚡ Limited spots this month — 50,000+ patients already started
Paid partnership · Prescription product · Not everyone qualifies · Results vary
Real patients. Real results.
Join 50,000+ patients who transformed their lives with GLP-1 medications
"I tried everything — keto, intermittent fasting, gym memberships. Nothing worked long-term. GLP-1 changed everything. I lost 47 pounds in 8 months and finally feel like myself again. The online process was so easy — I had my prescription in 2 days."
Jessica M., 38
Texas
-47 lbs
in 8 months
Compounded semaglutide
"At 52, my doctor said I was heading toward diabetes. I started tirzepatide through a telehealth program and lost 62 pounds. My A1C is back to normal, my blood pressure dropped, and I'm off two medications. Wish I'd done this years ago."
David R., 52
Florida
-62 lbs
in 11 months
Tirzepatide (Zepbound)
"I was skeptical about doing this online, but the whole process was professional and easy. My provider answered all my questions, and the medication arrived in 4 days. I've lost 38 pounds and finally have energy to play with my kids again."
Aisha K., 34
California
-38 lbs
in 6 months
Compounded semaglutide
Results vary. These testimonials reflect individual experiences and are not typical. Weight loss depends on diet, activity, and adherence to medication.
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