GLP-1 Dosage Chart: Complete Dosing Schedule for All Medications
Complete GLP-1 dosage chart: titration schedules, maintenance doses, and injection timing for all GLP-1 medications.
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Quick answer: GLP-1 dosage chart
GLP-1 medications use gradual titration schedules to minimize side effects. Wegovy (semaglutide) titrates from 0.25 mg to 2.4 mg weekly over 16 weeks. Zepbound (tirzepatide) titrates from 2.5 mg to 15 mg weekly over 20 weeks. Saxenda (liraglutide) titrates from 0.6 mg to 3 mg daily over 5 weeks. Foundayo (orforglipron) titrates from 3 mg to 36 mg daily over approximately 24 weeks. Always follow your provider's prescribed schedule.
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Start consultationSemaglutide (Wegovy) dosage chart
| Week | Dose | Frequency |
|---|---|---|
| 1–4 | 0.25 mg | Once weekly |
| 5–8 | 0.5 mg | Once weekly |
| 9–12 | 1.0 mg | Once weekly |
| 13–16 | 1.7 mg | Once weekly |
| 17+ (maintenance) | 2.4 mg | Once weekly |
Tirzepatide (Zepbound / Mounjaro) dosage chart
| Week | Dose | Frequency |
|---|---|---|
| 1–4 | 2.5 mg | Once weekly |
| 5–8 | 5 mg | Once weekly |
| 9–12 | 7.5 mg | Once weekly |
| 13–16 | 10 mg | Once weekly |
| 17–20 | 12.5 mg | Once weekly |
| 21+ (maintenance) | 15 mg | Once weekly |
Note: Some patients maintain at 10 mg or 12.5 mg if 15 mg is not tolerated. See our tirzepatide dosage guide.
Liraglutide (Saxenda) dosage chart
| Week | Dose | Frequency |
|---|---|---|
| 1 | 0.6 mg | Once daily |
| 2 | 1.2 mg | Once daily |
| 3 | 1.8 mg | Once daily |
| 4 | 2.4 mg | Once daily |
| 5+ (maintenance) | 3.0 mg | Once daily |
Orforglipron (Foundayo) dosage chart
| Month | Dose | Frequency |
|---|---|---|
| 1 | 3 mg | Once daily |
| 2 | 6 mg | Once daily |
| 3 | 12 mg | Once daily |
| 4 | 24 mg | Once daily |
| 5+ (maintenance) | 36 mg | Once daily |
Oral semaglutide (Rybelsus) dosage
- Starting dose: 3 mg once daily for 30 days
- Maintenance dose: 7 mg or 14 mg once daily
- Must be taken on an empty stomach with no more than 4 oz of water
- Wait at least 30 minutes before eating or drinking
For Wegovy oral tablets (25 mg daily), no titration is required — the full dose is taken from day one. See our GLP-1 oral pill guide.
Missed dose guidance
| Medication | If You Miss a Dose |
|---|---|
| Wegovy, Ozempic | Take within 5 days. If more than 5 days, skip and resume normal schedule. |
| Zepbound, Mounjaro | Take within 4 days (Zepbound) or 5 days (Mounjaro). If past, skip and resume schedule. |
| Saxenda | Take as soon as remembered. Do not double up. If next dose is due, skip the missed one. |
| Rybelsus, Foundayo | Take as soon as remembered. Do not take two doses in one day. |
For more details, see our GLP-1 missed dose guide and titration schedule guide.
FAQ
What is the starting dose for Wegovy?
0.25 mg weekly for 4 weeks, increasing to 2.4 mg over 16 weeks.
What is the starting dose for Zepbound?
2.5 mg weekly for 4 weeks, increasing to 15 mg over 20 weeks.
How long does titration take?
16 weeks for semaglutide, 20 weeks for tirzepatide, 5 weeks for liraglutide, ~24 weeks for orforglipron.
What if I miss a dose?
Weekly injections: take within 4–5 days, otherwise skip. Daily medications: take as soon as remembered, do not double up.
Can I increase my dose faster?
No. Faster titration significantly increases side effects. Always follow your provider's schedule.
What is the maintenance dose?
Wegovy 2.4 mg/week, Zepbound 10–15 mg/week, Saxenda 3 mg/day, Foundayo 36 mg/day.
When is the best time to inject?
Weekly: same day each week, any time. Daily: same time each day. Rybelsus: empty stomach, 30 min fasting after.
Can I split my dose?
No. GLP-1 medications should not be split, divided, or shared. Take as a single unit.
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